As far as CO2 and human health, there absolutely is evidence which directly associates high levels of CO2 with human health concerns.
https://www.sciencedirect.com/science/article/pii/S036013232300358X
CO2 concentrations below 5000 ppm had no significant effect on the performance of simple cognitive tasks. However, the complex cognitive task performance showed a significant decrease at CO2 concentrations of 1000–1500 ppm and was also negatively impacted at 1500–3000 ppm. In addition, physiological responses (e.g., heart rate, HRV, and ETCO2) and psychological states (e.g., emotion, fatigue and sleepiness, and perceived air quality) were likely to be adversely affected by CO2 concentrations higher than 3000 ppm.
Now, these numbers are obviously higher than one would expect to see outdoors (thankfully). But as @Achim_AirGradient blog post he linked shows, we do see periods of time in places where CO2 levels outdoors are twice that of what you would normally expect. Example:
Lets not worry too much about the absolute values here and just use some round numbers. If you, as an example, have an outdoor CO2 level in your area of 450 ppm as measured by your AirGradient sensor. And you, as an example, also have an indoor reading of your other AirGradient sensor of 700ppm.This is within safe ranges. Your delta is about ~350ppm.
If the outdoor CO2 reading suddenly doubled to 900 ppm for several hours, the current ventilation systems you have in place in your house would no longer be able to keep up. Asuming the same ~350ppm delta here. You could begin seeing readings in your home closer to ~1200ppm, which would put you in the territory where you could begin to have health impacts.